The postoperative care of patients subjected to cardiac surgery frequently require a complete recovery with intravenous fluids, but crystalloid solutions like normal saline may increase the interstitial oedema, and it is also well known that fluid overload increases mortality.
Corporación de Fomento Asistencial del Hospital Universitario San Vicente de Paúl” (CORPAUL) (San Vicente de Paul University Hospital Corporation for the Promotion of Care) provided modelos de patios de casas the labeled solutions for this study. Preoperative risk factors, baseline characteristics, surgery times and heart-lung machine bypass times were similar in both groups (Table 1).

There were also evaluated days of hospital and ICU stay, hours of invasive and non-invasive mechanical ventilation, balance of fluids administered and eliminated, requirement of vasoactive and inotropic drugs, transfusion requirements and ICU readmission.
Considering the presence of various outcomes on the analysis and the dependence between some of them (bicarbonate, base excess), only differences with a P value below 0.01 were considered significant. Out of a total of 494 patients evaluated, 102 were included and assigned to the HS groups (51 patients) or NS (51 patients).
Likewise, the study intervention was limited to a sole bolus that in average represented 250cc of fluid. A total of 494 patients were admitted to the ICU from April 18, 2013 to January 20, 2015. The effect of excess fluid balance on the mortality rate of surgical patients: a multicenter prospective study.

The authors have obtained the written informed consent of the patients or subjects mentioned in the article. Furthermore, returning patients to the ICU was not necessary. Hypertonic versus near isotonic crystalloid for fluid resuscitation in critically ill patients.
Consequently, we conducted a randomized clinical trial to estimate the effect of a 7.5% saline (HS) infusion compared with a 0.9% saline (NS) over lactate values, hemodynamic and metabolic variables in the first 24 post-surgical hours of patients undergoing heart-lung machine bypass.

Secondary outcomes included heart rate, mean arterial blood pressure, central venous pressure, pulmonary wedge pressure, cardiac index, arterial pH, bicarbonate, hematocrit, base deficit, mixed venous oxygen saturation and oxygenation index (PaFi) into the same measurements time.
Comparar el efecto del salino hipertónico (SH) al 7.5% con respecto al salino normal (SN) del 0.9% en la depuración de lactato y la respuesta hemodinámica durante el primer día postoperatorio de pacientes con cirugía cardiovascular con circulación extracorpórea.
For lactate measurements, and also for all repeated measurements, we developed an analysis with a generalized estimating equation (GEE) model, assuming an interchangeable correlation between repeated measurements. NS, normal saline; HS, hypertonic saline. Copyright © 2019 Elsevier, en este sitio se utilizan Cookies excepto para cierto contenido proporcionado por terceros.